Restoration of the Majority of the Visual Spectrum by Using Modified Volvox Channelrhodopsin-1
نویسندگان
چکیده
منابع مشابه
Restoration of the Majority of the Visual Spectrum by Using Modified Volvox Channelrhodopsin-1
We previously showed that blind rats whose vision was restored by gene transfer of Chlamydomonas channelrhodopsin-2 (ChR2) could only detect wavelengths less than 540 nm because of the action spectrum of the transgene product. Volvox-derived channelrhodopsin-1, VChR1, has a broader spectrum than ChR2. However, the VChR1 protein was mainly localized in the cytoplasm and showed weak ion channel p...
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2014
ISSN: 1525-0016
DOI: 10.1038/mt.2014.81